The BMI consists of body weight and height, which are included in GNRI calculations,[7] and serum albumin level is often reduced in HCC patients.[28] Hypoalbuminemia has been proven to be a poor prognostic factor for a variety of malignancies,[29] the GNRI may more objectively reflect the weight change in tumor patients due to tumor consumption, hence we consider that it is necessary to assess the patient’s nutritional condition using GNRI and assess the influence of GNRI on prognosis on HCC patients receiving TACE. This evidence concerns the gene ALB and neoplasm.