Moreover, it reduced TCM syndrome scores and laboratory indicators and had no obvious adverse reactions.[6–8] Further studies revealed that Miao medicine Tongfengting decoction has anti-inflammatory effects by its ability to reduce serum uric acid level and inhibit cyclooxygenase-2 (COX-2) and xanthine oxidase (XOD) activities.[9,10] Currently, TCM uses a multi-component and multi-target approach; its mechanism of action in the treatment of gout remains unclear, requiring further clarification. This evidence concerns the gene PTGS2 and gout.