The results show that the signaling pathways involved in the 23 core targets included the Pathways in cancer, Lipid and atherosclerosis, Human cytomegalovirus infection, MAPK signaling pathway, PI3K-Akt signaling pathway.The results suggest that these pathways may be important signal transduction in the treatment of gout by Miao Gout Stopping Soup. The gene discussed is PIK3CB; the disease is atherosclerosis.