To test the hypothesis that the SARS-CoV-2 virus displays tropism not only to kidney cells, but also to renal cell carcinoma, we utilized the publicly available transcriptomic data sets deposited by The Cancer Genome Atlas project (TCGA) to assess the transcriptional levels of ACE2, TMPRSS2 and NRP1 mRNA in individual CCRCC, PRCC and CHRCC cases. This evidence concerns the gene TMPRSS2 and nonpapillary renal cell carcinoma.