To allow for high-throughput analysis of ACE2, TMPRSS2 and NRP1 protein expression in RCC, we stained tissue micro arrays (TMA) with 263 cases of CCRCC, 139 cases of PRCC, 18 cases of CHRCC and human kidney tissue as control with antibodies against ACE2, TMPRSS2 and NRP1. The gene discussed is TMPRSS2; the disease is nonpapillary renal cell carcinoma.