To allow for high-throughput analysis of ACE2, TMPRSS2 and NRP1 protein expression in RCC, we stained tissue micro arrays (TMA) with 263 cases of CCRCC, 139 cases of PRCC, 18 cases of CHRCC and human kidney tissue as control with antibodies against ACE2, TMPRSS2 and NRP1. This evidence concerns the gene TMPRSS2 and renal cell carcinoma.