However, while only 25% of patients with lymphoplasmacytic lymphoma (LPL) in the PROTEST 2.0 study was tested for HIV within 3 months [21], the previously identified standardized incidence ratio of LPL among PLHIV was 3.6 (95% CI 2.0–6.0) [27], highlighting likely missed opportunities for HIV diagnosis among patients with low-grade NHL subtypes. The gene discussed is LPL; the disease is lymphoplasmacytic lymphoma.