For class II genes, a haplotype with DRB1*13:02 and DQB1*06:04 is associated with susceptibility to KS in AIDS patients in the US and Italy (Dorak et al. 2005; Guerini et al. 2006; Masala et al. 2005), with PHN in Japan (Meysman et al. 2015), and a similar haplotype (DRB1*13:01 and DQB1*06:03) associated with higher IgG levels to HHV-6A (Engdahl et al. 2019). The gene discussed is HLA-DRB1; the disease is Kaposi's sarcoma.