Hypertension and proteinuria were substantially increased in patients treated with angiogenesis inhibitors and EGFR‐TKIs (hypertension: RR = 4.88, 95% CI: 3.49–6.81, p < 0.001; proteinuria: RR = 12.83, 95% CI: 3.98–41.38, p < 0.001) (Table 3). Here, EGFR is linked to Hypertension.