For example, Domenis et al. reported that exosomes derived from SW480 (human colorectal adenocarcinoma cell line) cells contributed to transferring dsDNA fragments containing the entire coding sequence of both tumor protein p53 (TP53) and KRAS proto-oncogene (KRAS) genes, harboring the TP53 c.818G > A and KRAS c.35G > T typical mutations. Here, TP53 is linked to colorectal adenocarcinoma.