In contrast, the knockdown of KMT2B significantly decreased the growth rate after 15 days of tumor growth, resulting in a 43% reduction in tumor weight (0.22 ± 0.085 g vs. 0.39 ± 0.089 g, p < 0.05) at the time of sacrifice (21 days post-inoculation) (Fig. 4G-I). The gene discussed is KMT2B; the disease is neoplasm.