Although, our main goal was not to decipher the mechanism involving NDRG1 stabilization by active GSK3β driven by TGFβ signaling; however, our data provide a different perspective about the positive regulation of NDRG1 by GSK3β to mediate mechanisms of tumor progression driven by TGFβ that must be deeply investigated. The gene discussed is NDRG1; the disease is neoplasm.