BST2 and colonic neoplasm: For the pathways annotated by GO biological process analysis, some of the upgraded pathways enriched in BST2-high colon cancer were as follows: immune response pathways, such as activation of immune response, adaptive immune response, adaptive immune response based on somatic recombination of immune receptors built from the immunoglobulin superfamily domain and alpha-beta T-cell activation (Figure 3B).