VEGFA and cancer: Compared to the response of MPC tumors to [PRRT] monotherapy, [ET + PRRT] combination therapy most prominently induced positive enrichment in 'cancer central carbon metabolism', 'glycolysis', 'transcriptional misregulation in cancer', 'apoptosis', 'TGF-beta signaling', and 'VEGF signaling', and caused negative enrichment in the 'Fanconi anemia pathway' and in 'homologous recombination' (Table 3).