What is more, the genes expression of MAPK, ELAVL1, RAB14, KLF9, ARF1, ARFGAP1, ATG7, ABCA7, SFT2D2, E2F2, MAPK7, and UHRF1 were both significantly decreased in PD (Figure 6(b)). Here, E2F2 is linked to Parkinson disease.