Further, we also verified that the expression of GRID2, PADI4, RIPK2, CUL4B, BCL6, MRPS31, GPI, and MAP 2 K1 were both significantly increased, and levels of MAPK, ELAVL1, RAB14, KLF9, ARF1, ARFGAP1, ATG7, ABCA7, SFT2D2, E2F2, MAPK7, and UHRF1 were both significantly decreased in PD. Here, E2F2 is linked to Parkinson disease.