GRPR and cancer: The clinical relevance of our target-specific nanoplatforms for the delivery of anticancer Pt(IV) prodrugs arises from the overexpression of GRPR in several human cancers not effectively treated with cisplatin and related Pt(II) derivatives such as glioblastoma, prostate, colon, pancreas, breast, small cell lung, non-small cell lung (NSCL) and ovarian cancers 34, 35.