Some precautions can prevent hypoglycemia during exercise and increase the safety of diabetics and those who use insulin, including informing supervisors/counselors and their exercise partners about their clinical condition; Obtaining easy and quick access to fast-absorbing carbohydrates; capillary blood glucose monitoring before, during and after exercise; paying attention to possible symptoms of hypoglycemia [5], consider these suggestions also for people with type 2 diabetes who use insulin or sulfonylureas. The gene discussed is INS; the disease is type 2 diabetes mellitus.