Hyperammonemia increased membrane expression of the NR2B subunit of NMDA receptors (151 ± 8%, p < 0.0001) (Fig. 9A) and of the GluA2 subunit of AMPA receptors (150 ± 10%, p < 0.001) (Fig. 9C) and reduced membrane expression of the GluA1 subunit of AMPA receptors (67 ± 5%, p < 0.0001) (Fig. 9B) in the hippocampal slices. This evidence concerns the gene GRIN2B and Hyperammonemia.