We performed selections by yeast surface display against four established human tumor antigens: NY-ESO1/HLA-A*02:01 (ref. 28) (Fig. 5c), MART1 (A2L)/HLA-A*02:01 (ref. 29) (Fig. 5d), gp100 (A9V)/HLA-A*02:01 (ref. 30) (Fig. 5e) and KRAS/HLA-A*02:01 (ref. 31) (Fig. 5f). The gene discussed is PMEL; the disease is neoplasm.