Assessment of serum LncRNA-PAX8-AS1, LAIR-2 mRNA, and LAIR-2 protein levels in clinical and subclinical hypothyroid patients carrying different SNP genotypes was performed in order to study the mechanistic role of rs4848320, rs1110839, and rs2287828 in hypothyroidism (Fig. 2). The gene discussed is LAIR2; the disease is hypothyroidism.