AAA lesions from Apoe−/−Rorafl/flIl7rCre/+ mice also showed more media cell apoptosis, less lesion media Myh11‐positive SMC contents and lesion collagen‐I deposition than those of Apoe−/−Il7rCre/+ control mice (Figure S7B–D, Supporting Information), although both Apoe−/−Rorafl/flIl7rCre/+ and Apoe−/−Il7rCre/+ control mice showed similar systolic, diastolic, and mean blood pressure increases after AAA development (Figure S7E, Supporting Information). This evidence concerns the gene APOE and triple-A syndrome.