Considering SARS-CoV-2 S contained the furin cleavage site [24], 90 K may recognize and interfere furin cleavage of SARS-CoV-2 S. As in the case of 90 K restricting HIV-1 infection [9], a direct binding verification is also needed amongst LGALS3BP/90 K, furin, and SARS-CoV-2 S in future work. This evidence concerns the gene LGALS3BP and HIV-1 infection.