In contrast, there were no significant associations with fibrosis progression in a cohort of NASH patients (GSE49541) or HCV load, although a non-significant positive tendency was observed between YBX1 expression and disease progression and survival in patients with HCV-related cirrhosis (GSE15654) (figure 8E–H). Here, YBX1 is linked to metabolic dysfunction-associated steatohepatitis.