DGAT1 and neoplasm: It has been shown that in 3D tumor spheroids and in vivo, DGAT inhibition induces significant cytotoxic effects, especially when combined with dietary long-chain PUFAs (LC-PUFAs), implicating the combination of diet (LC-PUFAs) and DGAT inhibitor (DFATi) administration as a highly relevant therapeutic combination to induce ferroptosis (85).