We characterized the skewed distribution of γδ T cells with an inversion in the proportion of the Vδ1/Vδ2 T cell subset in AML patients, and we found a significant increase in the PD-1+Foxp3+ γδ T cell subset in AML, which was associated with poor clinical outcome (Figure 5). This evidence concerns the gene FOXP3 and acute myeloid leukemia.