Univariate analysis showed that there were significant differences in age, history of hepatectomy, tumor burden group, SACE level, Bead diameter, alkaline phosphatase (AKP), gamma glutamyl-transpeptidase (GGTP), and platelet (PLT) count between HCC patients with and without bile duct injury after DEB-TACE (all P <0.05; Table 1). This evidence concerns the gene GGTLC1 and hepatocellular carcinoma.