TP53 and non-small cell lung carcinoma: Some somatic variants of certain genes, including EGFR, ALK, ROS1, KRAS, BRAF, RET, MET, ERBB2, NTRK, TP53, and PI3KCA, have been identified as common driver mutations in the NSCLC National Comprehensive Cancer Network (NCCN) guidelines (version 3.2022).