Gene expression analysis of 31 m6A regulators between TCGA NSCLC samples and adjacent control samples showed that most regulator genes were significantly overexpressed in NSCLC tissues, especially reader genes (IGF2BP1, IGF2BP2, and IGF2BP3) from the IGF2BPs family (Figure 1D). The gene discussed is IGF2BP1; the disease is non-small cell lung carcinoma.