Quercetin was found to inhibit resistance to docetaxel in prostate cancer through the PI3K/AKT signaling pathway (48), to inhibit the AKT/CSN6/C-MYC signaling pathway and induce apoptosis of HT-29 colon cancer cells (49), and to increase the sensitivity of ovarian cancer cells to chemotherapy (50). Here, AKT1 is linked to colonic neoplasm.