In recent years, researchers have focused on developing systemic inflammatory biomarkers to predict the prognosis of patients with AP, including RDW (20), Neutrophil/Lymphocyte Ratio (NLR) (21), RDW/Platelet Ratio (RPR) (22), Glycemic/Lymphocyte Ratio (GLR) (23), C-Reactive Protein/Albumin ratio (24), etc. LAR has been applied as a new predictor for Sepsis, Heart Failure and Acute Respiratory Failure (25–27) with a good prediction of mortality. The gene discussed is CRP; the disease is acute respiratory failure.