SPIB and cancer: Among these prognostic genes, we further identified the following positively correlated MET, ITGA3, EREG, PLOD2, EMP1, CD44 HMGA2, TGM2, GAPDH, IL31RA, CGB7, CDH3, and negatively correlated PRDM16, PPARGC1A, CAPN6, SPIB, TOX3, and FGFR4 associated with the different cancer cell functions listed in Table 1, while Kaplan Meier curves signifying their prognostic association are presented in Figures 4 and SF 2.