In the IBD-induced mice treated with PBS, the level of T-bet+ or IFN-γ+ CD4+ T cells and ROR-γt+ or IL-17A+ CD4+ T cells in the spleen and mesenteric lymph node (mLN) were substantially higher than those in the healthy control (Supplementary Figures S7A-D). Here, IL17A is linked to inflammatory bowel disease.