The most important protein targets based on its degree from the C-T-P-D network were TNF, MAPK1, MAPK3, IL6, IL1B, AKT1 and CASP3 and the most important pathways associated with these protein targets were “Pathways in cancer”, “IL-17 signaling pathway”, and “Human cytomegalovirus infection”. The gene discussed is CASP3; the disease is cancer.