CHB infection is classified into four clinical phases according to serum HBV DNA load, alanine aminotransferase (ALT) levels, and HBeAg status: the HBeAg-positive immune tolerant (IT) and immune active (IA) phases, as well as the HBeAg-negative inactive carrier (IC) and hepatitis phases (ENEG) (4). The gene discussed is GPT; the disease is hepatitis A virus infection.