These findings seem to be consistent with clinical studies, as NAFLD patients have higher levels of both ROS and lipid peroxidation products than healthy controls, while lower levels of antioxidant enzymes, such as superoxide dismutase (SOD) and catalase (CAT), and lower levels of antioxidant compounds, such as glutathione (GSH) (66, 67). The gene discussed is CAT; the disease is metabolic dysfunction-associated steatotic liver disease.