In GSE42352 dataset, it was also found that LPAR5 had higher expression in non-metastasis patients than metastasis patients (P=0.019) (Figure 9C), and the expression of LPAR5 was much higher in tumor biopsy than cell line, mesenchymal stem cell and osteoblast (P<0.001) (Figure 9D), which was consistent with the results we found above. This evidence concerns the gene LPAR5 and neoplasm.