PDCD1 and acute myeloid leukemia: To further evaluate the relationship between TRP score and immunotherapy, we calculated the correlation between the TRP scores and the expression level of four classical immune checkpoints, and we found that the score was correlated with PDCD1 (R = 0.37, p = 2.5 × e−6), CTLA4 (R = 0.44, p = 1.5 × e−8), CD274 (R = 0.46, p = 2.5 × e−9), and PDCD1LG2 (R = 0.48, p = 7.1 × e−10), which can provide an important reference for the immunotherapy of AML (Figure 6B).