Similarly, normalization of the dosage of Dyrk1A in the partial trisomic Ts65Dn DS mouse model (Ts65Dn +/+/− with only two copies of Dyrk1A), rescues granular and Purkinje cell densities and the size of the granular and molecular layers (García-Cerro et al., 2018). This evidence concerns the gene DYRK1A and Dravet syndrome.