Earlier genome-wide association studies reported that single nucleotide polymorphisms (SNPs) present in the first intron of the fat mass and obesity-associated gene (FTO) increase the risk of obesity by 1.2-fold and are associated with an average increase in body mass index (BMI) of 0.39 kg/m2 (body weight 1,130 g) (5). Here, FTO is linked to obesity due to melanocortin 4 receptor deficiency.