In the Local-SCLC cohort, macrophages, M1 macrophages, and Th1 cells were found to be higher in the TGFB-HIGH group than in the TGFB-LOW group, while Th2 cells, Tregs, and M2 macrophages were lower than in the TGFB-LOW group (all p < 0.05, Figure 5(a)). The gene discussed is TGFB1; the disease is small cell lung carcinoma.