It is interesting to note that a recent study identified RPL13 having a role in the induction and activation of the promoters of the nuclear factor-κB (NF-κB) and interferon-β (IFN-β) genes, and the expression and protein secretion of the antiviral factor IFN-β and proinflammatory cytokine interleukin-6 in the course of foot-and-mouth disease viral response (Guan et al., 2021). This evidence concerns the gene NFKB1 and foot and mouth disease.