A. muciniphila is able to produce SCFAs as a result of mucin degradation (Ottman et al., 2017) and can counteract the onset of obesity by reducing appetite, energy intake, systemic inflammation, and blood pressure, and improve the gut barrier function (Le Blanc et al., 2017; Chambers et al., 2018). This evidence concerns the gene MUC5AC and obesity due to melanocortin 4 receptor deficiency.