MECP2 and neurodevelopmental disorder: MECP2 mutations have also been associated with a wide range of other neurodevelopmental diseases, including X-linked mental retardation, and autism, representing that mutation in MECP2 has extensive consequences and leads to various neurodevelopmental disorders (Bostick et al., 2007, Amir et al., 1999, Gonzales and LaSalle, 2010).