Hepatic steatosis ↓, serum TC ↓, HDL-C ↓. TNF-α↓, IL-6 ↓, IL-1β↓. A tendency to reduce the ratio of Firmicutes to Bacteroidetes. Relative abundance of Bacteroides intestinalis ↑, Bacteroides sartorii ↑, Lactobacillus johnsonii ↑. The gene discussed is TNF; the disease is fatty liver disease.