Combined with a significant increasein epithelial markers such as Desmoglein, alphaE-catenin,Collagen alpha-1(IV), and a decrease in mesenchymal markers such as Slug, Snail, Vimentin, Mucin 1, Zinc finger E-box-bindinghomeobox 1 (ZEB1), these results demonstrate a loss of epithelialand gain of mesenchymal characteristics which is a known feature ofthe APC-mutant tumor cells. Here, APC is linked to neoplasm.