Then, it revealed that in sepsis patients with T2DM, MAP (0.928,0.906-0.950), PLT (0.995,0.992-0.999), HDL (0.009,0.002-0.036), apoE (0.988,0.979-0.997), and cystatin C (1.960,0.360-2.826) were independent predictors for MAKE30 (Table 3). The gene discussed is APOE; the disease is Sepsis.