Taking the occurrence of renal impairment (β2-MG>2.4 mg/L) as the dependent variable, and taking age, BMI, total cholesterol, hypertension course, LDL-C, Alb, HS-CRP, HDL-C, eGFR, SUA, TyG index, BUN, mALB, and Sex as the independent variables, a multivariate Logistic regression analysis was performed. The gene discussed is ALB; the disease is hypertensive disorder.