The relationship between the TyG index and early renal injury indicators was analyzed by Multivariate linear regression with serum β2-MG and serum cystatin C as dependent variables and age, BMI, TC, hypertension course, LDL-C, Alb, HS-CRP, HDL-C, eGFR, SUA, TyG index, BUN, mALB and Sex as independent variables. This evidence concerns the gene CST3 and hypertensive disorder.