Among the top decreased proteins in infertile IOF, the expression of Small RNA binding exonuclease protection factor la (SSB), Myosin heavy chain 10 (MYH10), Heat shock protein family A (Hsp70) member (HSPA)9 and WD repeat domain 61 (WDR61) was significantly decreased in infertile organoid cells compared to fertile organoid cells respectively (Figure 6B). This evidence concerns the gene SSB and Infertility.