ACTA2 and liver cancer: This was corroborated by interrogation of the publicly available (TCGA) human liver cancer dataset on the cBioPortal website (http://www.cbioportal.org/), where SULF2 expression in HCC correlated strongly in a highly significant fashion with the myofibroblast markers vimentin, αSMA (ACTA2), COL1A1, COL1A2, and TIMP2 (online suppl.