However, after the LPS-incubated HPAEpiCs (model group) were treated with inositol, the LC3B fluorescence signal was obviously enhanced, (Figure 2(b) and Supplementary Figure 1A), suggesting that inositol could activate autophagy in LPS-induced HPAEpiCs to alleviate ARDS-caused lung injury. This evidence concerns the gene MAP1LC3B and acute respiratory distress syndrome.