SQSTM1 and pulmonary fibrosis: It was recently shown that autophagy inhibition-mediated EMT could augment local myofibroblast differentiation via p65/RELA-mediated transactivation of Snail2 caused by increased p62/SQSTM1 expression in pulmonary fibrosis, suggesting that autophagy could inhibit EMT to extenuate pulmonary fibrosis [29].