This study evaluated the effects of the overexpression of Tau and its pseudo-phosphorylated form on the phosphorylation of ribosomal protein S6 and eIF4E binding protein (4EBP), the downstream factors of mTOR, which are reportedly elevated in AD (Tramutola et al., 2015; Sun et al., 2020). The gene discussed is RPS6; the disease is Alzheimer disease.