SCG2 and congenital bilateral aplasia of vas deferens from CFTR mutation: Functional enrichment analysis in this study showed that SCG2 was involved in a variety of biological functions in the process of valve calcification, such as granulocyte chemotaxis, leukocyte migration, regulation of epithelial cell apoptotic process, epithelial mesenchymal transformation (Supplementary Table S2), which provided direct clues to how SCG2 plays a biological role in CAVD.