The Enhanced Liver Fibrosis (ELF) test is a commercially available algorithm that includes three serum biomarkers: hyaluronic acid (HA), the N-terminal pro-peptide of collagen type III (PIIINP), and tissue inhibitor of metalloproteinase-1 (TIMP1) (Rosenberg et al., 2004; Guha et al., 2008). The gene discussed is TIMP1; the disease is Hepatic fibrosis.